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Other Writing ...
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If you would like to contact me, you can at lesh@leshatton.org
or through the contact points on each page which automatically insert a reference.
About the Fundamental Law of Inequality: June 2022
My co-author Greg Warr and I finally published our book on this subject:
"Exposing Nature's Bias: the Hidden Clockwork behind Society, Life and the Universe."
It is the culmination of more than 10 years of research and unifies the emergent properties of
many systems but most notably, the genome.
Here's some of the story so far.
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June 2022
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May 2022
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Watch how the universal symmetry of DNA gradually degrades as genomes decline
in size from the extraordinary axolotl, down to the viruses such as Covid-19
which are a million times smaller.
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October 2019
Strong evidence of an information-theoretical conservation principle linking all discrete systems
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A complete general theory of why disparate discrete systems such as the proteome
and collections of computer software share identical properties such as their
length distributions. There's a lot more to come.
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Download
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CoHSI V; Identical multiple scale-independent systems within genomes and computer software
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The genome and hexadecimal software dumps have exactly the same information properties.
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Download
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CoHSI IV; Unifying Horizontal and Vertical Gene Transfer - is Mechanism Irrelevant ?
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Shows that CoHSI correctly predicts the rate at which proteins are copied across all domains of life, demonstrating that viruses are fundamental to this process.
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CoHSI III: Long proteins and implications for protein evolution
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Shows that the longest protein depends only on the size of the protein aggregation and demonstrates that this leaves a recognisable footprint in the phylogenetic tree including evidence of a previously undocumented mass extinction.
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CoHSI II; The average length of proteins, evolutionary pressure and eukaryotic fine structure
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Why protein average length is highly conserved and unusual fine structure identified in the Eukaryota.
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CoHSI I; Detailed properties of the Canonical Distribution for Discrete Systems such as the Proteome
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A comprehensive exploration of the properties of the CoHSI equation.
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Download
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September 2017
Conservation of Hartley-Shannon Information (CoHSI) in discrete systems
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The length distribution of discrete systems such as the complete Proteome,
collections of Software in any language and digital Music all obey
the following equation
which for components large compared with their alphabet asymptotes to
a power-law
It has nothing to do with natural selection, human volition or any other action
other than the natural behaviour of large random systems. It is an
emergent property and in important ways,
software and protein structural properties are therefore identical.
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Download
Heiland Lecture, CSM, Golden CO, 07-Mar-2018
NIST Lecture, Boulder CO, 06-Mar-2018
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May 2015
Conservation of Information in Proteins
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In proteins, CoHSI predicts the remarkable constancy of average
protein length and also why very long proteins exist.
PLOS ONE download
Like all my recent work, complete computational reproducibility packages
are provided which are capable of reproducing each diagram, table and statistical
result using entirely open source. As an example, for this paper it can
be found at
Reproducibility package
and a tutorial in how to build reproductibility packages is given here.
How to build reproducibility packages
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April 2014
Software's Hidden Clockwork
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Just like proteins, all software systems have
a hidden clockwork which forces them into the same component size distribution
whatever they do, whoever wrote them and whatever technology or
language was used. Just watch as 100 million lines of C, C++, Java, Fortran,
Ada and Tcl-Tk asymptote to the CoHSI distribution in 1/2 million line chunks.
IEEE TSE preprint
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